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Jeremy C. Borniger, PhD

I am a neuroscientist funded by the NIH BRAIN Initiative currently working at Stanford University as a post-doc in Luis de Lecea’s Lab. I was born in Washington, D.C. and grew up in the district until I went off to college where I majored in biological anthropology, at Indiana University - Bloomington. Following graduation, I worked as the assistant project director at the Semliki Chimpanzee Project in Western Uganda, where I worked to combat poaching in the region, habituate the chimpanzees, and collect ecological data. Fascinated by animal behavior, I decided to switch to neuroscience for my graduate education. This allowed me to causally test my hypotheses via direct manipulation of the brain. I wrote a short piece in Science detailing my struggles with switching fields. 

In graduate school (Randy Nelson's lab at The Ohio State University), I became interested in one of the most important behaviors for all animals on the planet: sleep. Chronic sleep problems affect approximately 10-20% of people in the developed world, resulting in an economic burden of over $100 billion. 

Cancer causes systemic disruption. My work aims to understand how the brain and cancer talk to each other, leading to changes in sleep, behavior, resistance to treatment, and tumor progression. (Borniger & Nevarez, 2019)

Cancer causes systemic disruption. My work aims to understand how the brain and cancer talk to each other, leading to changes in sleep, behavior, resistance to treatment, and tumor progression. (Borniger & Nevarez, 2019)

Despite the prevalence and cost of these problems, a basic understanding of how sleep and arousal work, on a circuit/network level, remains elusive. For my dissertation, I investigated how non-metastatic cancer directly alters sleep via modulation of specific neurons within the hypothalamus (see CV). The bridging of neuroscience with cancer research was exciting to me, and I loved using methods from multiple fields to answer my questions. During my post-doc, I aim to continue this line of research, and expand into other areas. Access to cutting-edge tools allows me to dissect how cancer interacts with the brain, how brain stimulation alters the immune system, and how 'local clocks' in the brain alter sleep and behavior.

Please visit the Research section to see all my active projects. 

IMPORTANT: Visitors are welcome to use any media on this site, as long as the author (Jeremy C Borniger, PhD), is credited. Please send an email (jcbornig@stanford.edu) for express consent.

Banner image: Slices from somatostatin-cre/Ai14 mice, male section on right, female section on left. (credit: Jeremy Borniger)

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